Bridging the Gap: Virus Long-Distance Spread via Tunneling Nanotubes
نویسندگان
چکیده
منابع مشابه
Influenza virus exploits tunneling nanotubes for cell-to-cell spread
Tunneling nanotubes (TNTs) represent a novel route of intercellular communication. While previous work has shown that TNTs facilitate the exchange of viral or prion proteins from infected to naïve cells, it is not clear whether the viral genome is also transferred via this mechanism and further, whether transfer via this route can result in productive replication of the infectious agents in the...
متن کاملBridging the Gap between Distance and Generalization
Distance-based and generalisation-based methods are two families of artificial intelligence techniques that have been successfully used over a wide range of real-world problems. In the first case, general algorithms can be applied to any data representation by just changing the distance. The metric space sets the search and learning space, which is generally instance-oriented. In the second cas...
متن کاملLong distance tunneling
Quantum tunneling between two potential wells in a magnetic field can be strongly increased when the potential barrier varies in the direction perpendicular to the line connecting the two wells and remains constant along this line. A periodic structure of the wave function is formed in the direction joining the wells. The resulting motion can be coherent like motion in a conventional narrow ban...
متن کاملLong-distance interferon signaling within the brain blocks virus spread.
UNLABELLED Serious permanent neurological or psychiatric dysfunction may result from virus infections in the central nervous system (CNS). Olfactory sensory neurons are in direct contact with the external environment, making them susceptible to infection by viruses that can enter the brain via the olfactory nerve. The rarity of full brain viral infections raises the important question of whethe...
متن کاملControl of long-distance cell-to-cell communication and autophagosome transfer in squamous cell carcinoma via tunneling nanotubes
Tunneling nanotubes (TnTs) are thin channels that temporally connect nearby cells allowing the cell-to-cell trafficking of biomolecules and organelles. The presence or absence of TnTs in human neoplasms and the mechanisms of TnT assembly remains largely unexplored. In this study, we have identified TnTs in tumor cells derived from squamous cell carcinomas (SCC) cultured under bi-dimensional and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Virology
سال: 2020
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.02120-19